22 May 2015 | Online since 2003



First TB skin test differentiates vaccinated and unvaccinated animals


New field trials have begun of a tuberculosis skin test based on bionanoparticle technology.

The PolyBatics Assign-bTB product is a DIVA (Differentiate Infected from Vaccinated Animals) TB skin test, the first such test to be able to differentiate unvaccinated animals from those vaccinated against bovine TB.

PolyBatics said the same antigen-presenting biobead technology is also being developed to produce a similar human TB skin test as well as new TB vaccines for animal and human use that do not interfere with TB skin tests created using the same technology.

The field trial is being conducted over the next few months in New Zealand cattle under the leadership of TBfree New Zealand and the Hopkirk Research Institute. The DIVA skin test was developed in conjunction with Dr. Bryce Buddle, Adjunct Professor of Infectious Diseases, Hopkirk Research Institute and Principal Scientist, Infectious Diseases Team, AgResearch, using PolyBatics’ technology.

Dr. Paul Livingstone, Manager of TB Eradication and Research for TBfree New Zealand said, “We are pleased to be supporting this study using a cutting edge technology and in the process, reaffirming New Zealand’s place at the forefront of managing and eliminating tuberculosis in wild animals and in our farmed livestock.”

He continued, “The aim of the study is to compare the specificity of Assign-bTB, the reagent developed via PolyBatics’ technology, with the current tuberculin in selected non-infected herds and its sensitivity in infected herds. If successful, we expect use of Assign-bTB will reduce the number of false-positives to the skin test. This will reduce the need for re-testing which will, in turn, provide potential cost savings to the TB control program.”

“PolyBatics biobeads represent an ideal platform for either diagnostic or vaccine applications, given their unique ability to consistently display antigens of choice on the biopolymer nanobead surface and their low-cost single-step production,” said Tracy Thompson, PolyBatics Chief Executive Officer. He noted that PolyBatics had initiated a number of vaccine development programs over the past year, including programs in hepatitis, dengue fever and TB therapeutics.

Download




Comments


No comments posted yet. Be the first to post a comment

To post comment without approval login or register

Display name

Please enter your name

Email (optional)
Comment

Please enter your comment

Post Comment

Your comment submitted successfully.Please wait for admin approval.

Some error on your process.Please try one more time.



Jobs


12 May 2015
New ASSISTANT MANAGER - New Build
ASSISTANT MANAGER - New Build - Pen Y Bont Farm. The Pen Y Bont Farm is due to open in September 2015 and will operate under ...

15 May 2015
Counter/ Food Service Assistant
For example, nut, dairy or wheat allergies. To provide excellent customer service from food service counters in a busy presti...

5 May 2015
Farm Foreman
The position is ideally suited to a capable and talented Working Farm Foreman with people skills and the ability to manage ea...

21 May 2015
GIS Analyst
A position is currently available to join the existing Geographical Information Systems (GIS) Team responsible for assisting ...

12 May 2015
COMMANDERS SUPPORT STAFF
Title: Commanders Support Staff RPA ____ 398689 Series, Grade, Vacancy Number: S- 0303 -0 6 LAK VA1 5 RPA 398689 Location: La...



Top stories you may have missed
15 May 2015 | Arable

Scotland’s Rural Affairs Secretary Richard Lochhead is calling on the Europ...


15 May 2015 | Finance

As the country settles down following the turmoil of the general election, ...


14 May 2015 | Animal Health

New research from the Universities of Bristol and Cambridge has found that ...


13 May 2015 | Animal Health

A new publication to help farmers prevent sheep lameness and offer advice o...


12 May 2015 | Agri Safety

The Farmers’ Union of Wales is putting the spotlight on Liver fluke at next...


5 May 2015 | News

The UK is now third in the global rankings for utility-scale solar energy a...


29 April 2015 | Agri Safety

A recent Rural Watch demonstration and information event gave Farmers’ Unio...


24 April 2015 | Meat Processing

Retailers should confirm their commitments to sourcing UK lamb this season,...


15 April 2015 | Meat Processing

A leading retailer has apologised after selling imported lamb in a Borders ...


9 April 2015 | Finance

The time has come for landlords to expect to see reductions in farm rents, ...