01 July 2015 | Online since 2003

First TB skin test differentiates vaccinated and unvaccinated animals



3 April 2014 09:02:02|Animal Health,Cattle,News,Veterinary News

First TB skin test differentiates vaccinated and unvaccinated animals


New field trials have begun of a tuberculosis skin test based on bionanoparticle technology.

The PolyBatics Assign-bTB product is a DIVA (Differentiate Infected from Vaccinated Animals) TB skin test, the first such test to be able to differentiate unvaccinated animals from those vaccinated against bovine TB.

PolyBatics said the same antigen-presenting biobead technology is also being developed to produce a similar human TB skin test as well as new TB vaccines for animal and human use that do not interfere with TB skin tests created using the same technology.

The field trial is being conducted over the next few months in New Zealand cattle under the leadership of TBfree New Zealand and the Hopkirk Research Institute. The DIVA skin test was developed in conjunction with Dr. Bryce Buddle, Adjunct Professor of Infectious Diseases, Hopkirk Research Institute and Principal Scientist, Infectious Diseases Team, AgResearch, using PolyBatics’ technology.

Dr. Paul Livingstone, Manager of TB Eradication and Research for TBfree New Zealand said, “We are pleased to be supporting this study using a cutting edge technology and in the process, reaffirming New Zealand’s place at the forefront of managing and eliminating tuberculosis in wild animals and in our farmed livestock.”

He continued, “The aim of the study is to compare the specificity of Assign-bTB, the reagent developed via PolyBatics’ technology, with the current tuberculin in selected non-infected herds and its sensitivity in infected herds. If successful, we expect use of Assign-bTB will reduce the number of false-positives to the skin test. This will reduce the need for re-testing which will, in turn, provide potential cost savings to the TB control program.”

“PolyBatics biobeads represent an ideal platform for either diagnostic or vaccine applications, given their unique ability to consistently display antigens of choice on the biopolymer nanobead surface and their low-cost single-step production,” said Tracy Thompson, PolyBatics Chief Executive Officer. He noted that PolyBatics had initiated a number of vaccine development programs over the past year, including programs in hepatitis, dengue fever and TB therapeutics.

Download




Comments


No comments posted yet. Be the first to post a comment

To post comment without approval login or register

Display name

Please enter your name

Email (optional)
Comment

Please enter your comment

Post Comment

Your comment submitted successfully.Please wait for admin approval.

Some error on your process.Please try one more time.



Jobs


Start Date: 18 June 2015
Tractor Driver; permanent job on mixed farm in Devon

We have a great opportunity for a self starting careful tractor driver who is able to organise their own time. The role invol...


Start Date: 17 June 2015
First class stockman / tractor driver required for a job near Tenby, Wales

Permanent position for a first class stockman to take responsibility for all dairy young stock rearing, feeding dairy he...


Start Date: 18 June 2015
Experienced Telehandler Operator Jobs x 2 required by busy Suffolk contractor 

Two positions available for harvest work loading lime/fertiliser spreaders & moving straw. Telehandler ticket a big ...


Start Date: 11 June 2015
Tractor driver / combine driver required to help out with all harvest / autumn work on a 1700 ac arable farm. 

Tractor driver required for primary and secondary cultivations on a 1700 ac arable farm. Also relief combining and grain cart...


Start Date: 20 June 2015
Dairy assistant required for holiday cover for milking a 300 Holstein Friesian herd on family farm.  Near Inverurie, Aberdeenshire. 

Reliable person required for milking twice a day on a rota basis as part of a 3 man team. As well as being able to milk you w...





Top stories you may have missed
5 June 2015 | Cattle

A strong pound and increased red meat imports coupled with a plentiful dome...


5 June 2015 | Arable

Depression is affecting Wales' farming industry and there is a need to use ...


5 June 2015 | Arable

With just one week to go before the final judging and announcement of the w...


5 June 2015 | Finance

A rural law expert has highlighted the importance of good succession planni...


5 June 2015 | Farmshops

A south Yorkshire dairy farming family is pulling out all the stops to prom...


4 June 2015 | Finance

Predicting what is going to happen to wheat prices is a challenge, but in s...


4 June 2015 | Agri Safety

A Lancashire based livestock theft prevention scheme is aiming to go nation...


4 June 2015 | News

A female farmer has been recognised by the farming and conservation industr...


4 June 2015 | Finance

The new Conservative government appears to be preparing to implement cuts f...


4 June 2015 | Arable

The Rural Payments Agency (RPA) will have mobile support units at the follo...