A Murray-Darling management group says crops and stock in the basin will boom this year once flooding in Queensland's south-west subsides.
The Murray-Darling Basin Commission also says the widespread flooding will encourage drought-stricken animal species in the basin to breed.
Commission spokeswoman Wendy Craik says the Warrego River floods will see farmers along the Murray-Darling better off after the best rains in the region for 10 years.
"It'll enable graziers to have a good start to this year," she said.
"In terms of cotton farmers, there's a fair amount of water harvesting going on.